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Understanding Hyaluronic Acid and Polynucleotide Injections

Published on July 28, 2026

The injections used in aesthetic medicine cover several families of products with different goals. Understanding these differences helps you have a more informed conversation with a doctor during a consultation, before any treatment decision.

Hyaluronic acid, a molecule naturally present in the skin

Hyaluronic acid is a molecule naturally found in the skin, where it contributes to its hydration and volume. In aesthetic medicine, synthetic hyaluronic acid gels are used, injected locally according to protocols defined by the doctor after a clinical examination. The areas treated, the volumes used and the injection technique are always determined on a case-by-case basis, according to each patient's anatomy and request.

Skinboosters, a different approach

Skinboosters are also based on hyaluronic acid, but in a form and with an injection technique different from those used for volume restoration. Their goal is to act on skin quality and hydration rather than volume.

Polynucleotides

Polynucleotides are another family of injectable products, distinct from hyaluronic acid, used in aesthetic medicine for their specific properties on skin quality. As with any injectable treatment, their indication is assessed individually by the doctor.

Why the consultation always comes before the injection

Whatever product is being considered, a prior medical consultation is essential. It allows the doctor to examine the area concerned, check for the absence of contraindications, explain how the procedure unfolds, its usual after-effects and its limits, and build a protocol with the patient that is genuinely tailored to their situation rather than a standardised response.

Results that vary from person to person

As with any medical procedure, the results of an injection vary from person to person depending on many individual factors (skin type, anatomy, lifestyle, etc.). No serious practitioner can guarantee an identical result for every patient: this is precisely why the consultation and personalised diagnosis are an essential step, not a mere formality.

General information, not medical advice. This article is intended for general information purposes and does not replace a personalised medical consultation. Only a consultation with a doctor can assess your situation and define a suitable protocol. Book an appointment.